
Dexamethasone (DHAP)
CAS No. 50-02-2
Dexamethasone (DHAP)( DHAP )
Catalog No. M14675 CAS No. 50-02-2
Dexamethasone (DHAP) is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
500MG | 37 | In Stock |
![]() ![]() |
1G | Get Quote | In Stock |
![]() ![]() |
Biological Information
-
Product NameDexamethasone (DHAP)
-
NoteResearch use only, not for human use.
-
Brief DescriptionDexamethasone (DHAP) is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects.
-
DescriptionDexamethasone (DHAP) is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects(In Vitro):MK-3207 (0.3, 0.6, 1.1, 2.3, 4.5, 9.0 nM; 30 min) potently blocks human α-CGRP-stimulated cAMP responses in human CGRP receptor-expressing HEK293 cells.(In Vivo):MK-3207 (0.3, 0.6, 2.1, 9.1, 21.2, 60.6 μg/kg; i.v.; single) inhibits CIDV in rhesus monkeys with EC50 and Emax values of approximately 0.8 nM and 81%.MK-3207 (10 mg/kg; p.o.; single) shows the CSF/plasma ratio is 2 to 3%.
-
In Vitro——
-
In Vivo——
-
SynonymsDHAP
-
PathwayEndocrinology/Hormones
-
TargetAnnexin A
-
RecptorAnnexin A1| Glucocorticoid Receptor| IL receptor| MRP1| iNOS| NR
-
Research AreaInflammation/Immunology
-
Indication——
Chemical Information
-
CAS Number50-02-2
-
Formula Weight392.46
-
Molecular FormulaC22H29FO5
-
Purity>98% (HPLC)
-
SolubilityEthanol: 6 mg/mL (15.28 mM); DMSO: 79 mg/mL (201.29 mM)
-
SMILESO=C1C=C[C@]2(C)[C@@]3(F)[C@@H](O)C[C@]4(C)[C@](C(CO)=O)(O)[C@H](C)C[C@@]4([H])[C@]3([H])CCC2=C1
-
Chemical Name(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Warne JP, et al. Am J Physiol Endocrinol Metab. 2006 Dec;291(6):E1264-73.
molnova catalog



related products
-
Hydrocortisone butyr...
Hydrocortisone 17-butyrate is an adrenocortico hormone.
-
Dexamethason acetate
Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs that has anti-inflammatory and immunosuppressant properties.
-
Hydrocortisone aceta...
Hydrocortisone acetate is a corticosteroid, used to decrease swelling, itching, and pain that is caused by minor skin irritations or by hemorrhoids.